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The MFF-SIRT1/3 axis, regulated by miR-340-5p, restores mitochondrial homeostasis of hypoxia-induced pulmonary artery smooth muscle cells

Mitochondrial dynamics and quality control play a central role in the maintenance of the proliferation–apoptosis balance, which is closely related to the progression of pulmonary arterial hypertension (PAH). However, the exact mechanism of this balance remains unknown. Pulmonary artery smooth muscle...

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Detalles Bibliográficos
Autores principales: Huang, Chun-Xia, Jiang, Zhi-Xin, Du, Da-Yong, Zhang, Zhi-Min, Liu, Yang, Li, Yun-Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042702/
https://www.ncbi.nlm.nih.gov/pubmed/35042949
http://dx.doi.org/10.1038/s41374-022-00730-w