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The MFF-SIRT1/3 axis, regulated by miR-340-5p, restores mitochondrial homeostasis of hypoxia-induced pulmonary artery smooth muscle cells
Mitochondrial dynamics and quality control play a central role in the maintenance of the proliferation–apoptosis balance, which is closely related to the progression of pulmonary arterial hypertension (PAH). However, the exact mechanism of this balance remains unknown. Pulmonary artery smooth muscle...
Autores principales: | Huang, Chun-Xia, Jiang, Zhi-Xin, Du, Da-Yong, Zhang, Zhi-Min, Liu, Yang, Li, Yun-Tian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042702/ https://www.ncbi.nlm.nih.gov/pubmed/35042949 http://dx.doi.org/10.1038/s41374-022-00730-w |
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