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Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, manifesting as the progressive development of fluid-filled renal cysts. In approximately half of all patients with ADPKD, end-stage renal disease results in decreased renal function. In this study, we u...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042704/ https://www.ncbi.nlm.nih.gov/pubmed/34980882 http://dx.doi.org/10.1038/s41374-021-00717-z |