Generation of heterozygous PKD1 mutant pigs exhibiting early-onset renal cyst formation

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, manifesting as the progressive development of fluid-filled renal cysts. In approximately half of all patients with ADPKD, end-stage renal disease results in decreased renal function. In this study, we u...

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Detalles Bibliográficos
Autores principales: Watanabe, Masahito, Umeyama, Kazuhiro, Nakano, Kazuaki, Matsunari, Hitomi, Fukuda, Toru, Matsumoto, Kei, Tajiri, Susumu, Yamanaka, Shuichiro, Hasegawa, Koki, Okamoto, Kazutoshi, Uchikura, Ayuko, Takayanagi, Shuko, Nagaya, Masaki, Yokoo, Takashi, Nakauchi, Hiromitsu, Nagashima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042704/
https://www.ncbi.nlm.nih.gov/pubmed/34980882
http://dx.doi.org/10.1038/s41374-021-00717-z

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