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What goes around comes around: Artificial circular RNAs bypass cellular antiviral responses

Natural circular RNAs have been found to sequester microRNAs and suppress their function. We have used this principle as a molecular tool and produced artificial circular RNA sponges in a cell-free system by in vitro transcription and ligation. Formerly, we were able to inhibit hepatitis C virus pro...

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Detalles Bibliográficos
Autores principales: Breuer, Janina, Barth, Patrick, Noe, Yannic, Shalamova, Lyudmila, Goesmann, Alexander, Weber, Friedemann, Rossbach, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042720/
https://www.ncbi.nlm.nih.gov/pubmed/35497503
http://dx.doi.org/10.1016/j.omtn.2022.04.017