Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction

HIV-1 must counteract various host restrictions to establish productive infection. SERINC5 is a potent restriction factor that blocks HIV-1 entry from virions, but its activity is counteracted by Nef. The SERINC5 and Nef activities are both initiated from the plasma membrane, where SERINC5 is packag...

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Detalles Bibliográficos
Autores principales: Li, Sunan, Li, Rongrong, Ahmad, Iqbal, Liu, Xiaomeng, Johnson, Silas F., Sun, Liangliang, Zheng, Yong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042822/
https://www.ncbi.nlm.nih.gov/pubmed/35474067
http://dx.doi.org/10.1038/s41467-022-30026-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042822/
https://www.ncbi.nlm.nih.gov/pubmed/35474067
http://dx.doi.org/10.1038/s41467-022-30026-y

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