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The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization

GADD45G, one of the genes containing the human-specific conserved deletion enhancer-sequence (hCONDEL), has contributed to the evolution of the human cerebrum, but its function in human neurons has not been established. Here, we show that the GADD45G/p38 MAPK/CDC25B signaling pathway promotes neurit...

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Detalles Bibliográficos
Autores principales: Kase, Yoshitaka, Sato, Tsukika, Okano, Yuji, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042895/
https://www.ncbi.nlm.nih.gov/pubmed/35497000
http://dx.doi.org/10.1016/j.isci.2022.104089