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Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2

Breakthrough infections by SARS-CoV-2 variants become the global challenge for pandemic control. Previously, we developed the protein subunit vaccine ZF2001 based on the dimeric receptor-binding domain (RBD) of prototype SARS-CoV-2. Here, we developed a chimeric RBD-dimer vaccine approach to adapt S...

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Detalles Bibliográficos
Autores principales: Xu, Kun, Gao, Ping, Liu, Sheng, Lu, Shuaiyao, Lei, Wenwen, Zheng, Tianyi, Liu, Xueyuan, Xie, Yufeng, Zhao, Zhennan, Guo, Shuxin, Tang, Cong, Yang, Yun, Yu, Wenhai, Wang, Junbin, Zhou, Yanan, Huang, Qing, Liu, Chuanyu, An, Yaling, Zhang, Rong, Han, Yuxuan, Duan, Minrun, Wang, Shaofeng, Yang, Chenxi, Wu, Changwei, Liu, Xiaoya, She, Guangbiao, Liu, Yan, Zhao, Xin, Xu, Ke, Qi, Jianxun, Wu, Guizhen, Peng, Xiaozhong, Dai, Lianpan, Wang, Peiyi, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042943/
https://www.ncbi.nlm.nih.gov/pubmed/35568034
http://dx.doi.org/10.1016/j.cell.2022.04.029