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Knockdown of GABA(A) alpha3 subunits on thalamic reticular neurons enhances deep sleep in mice
Identification of mechanisms which increase deep sleep could lead to novel treatments which promote the restorative effects of sleep. Here, we show that knockdown of the α3 GABA(A)-receptor subunit from parvalbumin neurons in the thalamic reticular nucleus using CRISPR-Cas9 gene editing increased th...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042958/ https://www.ncbi.nlm.nih.gov/pubmed/35473906 http://dx.doi.org/10.1038/s41467-022-29852-x |