Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing

Bloom syndrome (BS) is associated with a profoundly increased cancer risk and is caused by mutations in the Bloom helicase (BLM). BLM is involved in the nucleolytic processing of the ends of DNA double–strand breaks (DSBs), to yield long 3′ ssDNA tails that serve as the substrate for break repair by...

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Detalles Bibliográficos
Autores principales: Xue, Chaoyou, Salunkhe, Sameer J., Tomimatsu, Nozomi, Kawale, Ajinkya S., Kwon, Youngho, Burma, Sandeep, Sung, Patrick, Greene, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042962/
https://www.ncbi.nlm.nih.gov/pubmed/35473934
http://dx.doi.org/10.1038/s41467-022-29937-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042962/
https://www.ncbi.nlm.nih.gov/pubmed/35473934
http://dx.doi.org/10.1038/s41467-022-29937-7

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