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Elastase- and LPS-Exposed Cpa3(Cre/+) and ST2(-/-) Mice Develop Unimpaired Obstructive Pulmonary Disease

IL-33 and its receptor ST2, as well as mast cells and their mediators, have been implicated in the development of chronic obstructive pulmonary disease (COPD). However, whether mast cells and the ST2 receptor play a critical role in COPD pathophysiology remains unclear. Here, we performed repeated i...

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Detalles Bibliográficos
Autores principales: Cardenas, Eduardo I., Alvarado-Vazquez, Perla A., Mendez-Enriquez, Erika, Danielsson, Erik A., Hallgren, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043106/
https://www.ncbi.nlm.nih.gov/pubmed/35493481
http://dx.doi.org/10.3389/fimmu.2022.830859