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Elastase- and LPS-Exposed Cpa3(Cre/+) and ST2(-/-) Mice Develop Unimpaired Obstructive Pulmonary Disease
IL-33 and its receptor ST2, as well as mast cells and their mediators, have been implicated in the development of chronic obstructive pulmonary disease (COPD). However, whether mast cells and the ST2 receptor play a critical role in COPD pathophysiology remains unclear. Here, we performed repeated i...
Autores principales: | Cardenas, Eduardo I., Alvarado-Vazquez, Perla A., Mendez-Enriquez, Erika, Danielsson, Erik A., Hallgren, Jenny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043106/ https://www.ncbi.nlm.nih.gov/pubmed/35493481 http://dx.doi.org/10.3389/fimmu.2022.830859 |
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