PPARγ phase separates with RXRα at PPREs to regulate target gene expression

Peroxisome proliferator-activated receptor (PPAR)-γ is a key transcription activator controlling adipogenesis and lipid metabolism. PPARγ binds PPAR response elements (PPREs) as the obligate heterodimer with retinoid X receptor (RXR) α, but exactly how PPARγ orchestrates the transcriptional response...

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Detalles Bibliográficos
Autores principales: Li, Zhean, Luo, Lingling, Yu, Wenxia, Li, Ping, Ou, Danfeng, Liu, Jia, Ma, Hanhui, Sun, Qinhu, Liang, Aibin, Huang, Cheng, Chi, Tian, Huang, Xingxu, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043196/
https://www.ncbi.nlm.nih.gov/pubmed/35473936
http://dx.doi.org/10.1038/s41421-022-00388-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043196/
https://www.ncbi.nlm.nih.gov/pubmed/35473936
http://dx.doi.org/10.1038/s41421-022-00388-0

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