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PPARγ phase separates with RXRα at PPREs to regulate target gene expression
Peroxisome proliferator-activated receptor (PPAR)-γ is a key transcription activator controlling adipogenesis and lipid metabolism. PPARγ binds PPAR response elements (PPREs) as the obligate heterodimer with retinoid X receptor (RXR) α, but exactly how PPARγ orchestrates the transcriptional response...
Autores principales: | Li, Zhean, Luo, Lingling, Yu, Wenxia, Li, Ping, Ou, Danfeng, Liu, Jia, Ma, Hanhui, Sun, Qinhu, Liang, Aibin, Huang, Cheng, Chi, Tian, Huang, Xingxu, Zhang, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043196/ https://www.ncbi.nlm.nih.gov/pubmed/35473936 http://dx.doi.org/10.1038/s41421-022-00388-0 |
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