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Newly synthesised oxime and lactone derivatives from Dipterocarpus alatus dipterocarpol as anti-diabetic inhibitors: experimental bioassay-based evidence and theoretical computation-based prediction

Dipterocarpus alatus-derived products are expected to exhibit anti-diabetes properties. Natural dipterocarpol (1) was isolated from Dipterocarpus alatus collected in Quang Nam province, Vietnam; afterwards, 20 derivatives including 13 oxime esters (2 and 3a–3m) and 7 lactones (4, 5, 6a–6e) were semi...

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Detalles Bibliográficos
Autores principales: Phuong Thao, Tran Thi, Bui, Thanh Q., Thi Thanh Hai, Nguyen, Huynh, Lam K., Quy, Phan Tu, Bao, Nguyen Chi, Dung, Nguyen Thi, Chi, Nguyen Linh, Van Loc, Tran, Smirnova, Irina E., Petrova, Anastasiya V., Ninh, Pham Thi, Van Sung, Tran, Nhung, Nguyen Thi Ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043233/
https://www.ncbi.nlm.nih.gov/pubmed/35492788
http://dx.doi.org/10.1039/d1ra04461c