Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice

BACKGROUND & AIMS: The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here, we report that O-GlcNAcylation, an intracellular post-translational modification regulated by 2 enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a criti...

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Detalles Bibliográficos
Autores principales: Robarts, Dakota R., McGreal, Steven R., Umbaugh, David S., Parkes, Wendena S., Kotulkar, Manasi, Abernathy, Sarah, Lee, Norman, Jaeschke, Hartmut, Gunewardena, Sumedha, Whelan, Stephen A., Hanover, John A., Zachara, Natasha E., Slawson, Chad, Apte, Udayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043307/
https://www.ncbi.nlm.nih.gov/pubmed/35093590
http://dx.doi.org/10.1016/j.jcmgh.2022.01.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043307/
https://www.ncbi.nlm.nih.gov/pubmed/35093590
http://dx.doi.org/10.1016/j.jcmgh.2022.01.014

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