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Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice
BACKGROUND & AIMS: The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here, we report that O-GlcNAcylation, an intracellular post-translational modification regulated by 2 enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a criti...
Autores principales: | Robarts, Dakota R., McGreal, Steven R., Umbaugh, David S., Parkes, Wendena S., Kotulkar, Manasi, Abernathy, Sarah, Lee, Norman, Jaeschke, Hartmut, Gunewardena, Sumedha, Whelan, Stephen A., Hanover, John A., Zachara, Natasha E., Slawson, Chad, Apte, Udayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043307/ https://www.ncbi.nlm.nih.gov/pubmed/35093590 http://dx.doi.org/10.1016/j.jcmgh.2022.01.014 |
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