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Binding Specificity of ASHH2 CW Domain Toward H3K4me1 Ligand Is Coupled to Its Structural Stability Through Its α1-Helix

The CW domain binds to histone tail modifications found in different protein families involved in epigenetic regulation and chromatin remodeling. CW domains recognize the methylation state of the fourth lysine on histone 3 and could, therefore, be viewed as a reader of epigenetic information. The sp...

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Detalles Bibliográficos
Autores principales: Bril’kov, Maxim S., Dobrovolska, Olena, Ødegård-Fougner, Øyvind, Turcu, Diana C., Strømland, Øyvind, Underhaug, Jarl, Aasland, Rein, Halskau, Øyvind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043364/
https://www.ncbi.nlm.nih.gov/pubmed/35495628
http://dx.doi.org/10.3389/fmolb.2022.763750