Mitochondrial ATP synthase inhibitory factor 1 interacts with the p53–cyclophilin D complex and promotes opening of the permeability transition pore

The mitochondrial permeability transition pore (PTP) is a Ca(2+)-dependent megachannel that plays an important role in mitochondrial physiology and cell fate. Cyclophilin D (CyPD) is a well-characterized PTP regulator, and its binding to the PTP favors pore opening. It has previously been shown that...

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Detalles Bibliográficos
Autor principal: Guo, Lishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043413/
https://www.ncbi.nlm.nih.gov/pubmed/35337801
http://dx.doi.org/10.1016/j.jbc.2022.101858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043413/
https://www.ncbi.nlm.nih.gov/pubmed/35337801
http://dx.doi.org/10.1016/j.jbc.2022.101858

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