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Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer

Peritoneal metastasis (PM) is the main site of gastric cancer (GC) distant metastasis and indicates an extremely poor prognosis and survival. Hypoxia is a common feature of peritoneal metastases and up-regulation of hypoxia inducible factor 1 alpha (HIF-1α) may be a potential driver in the occurrenc...

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Detalles Bibliográficos
Autores principales: Lin, Zaihuan, Song, Jialin, Gao, Yuke, Huang, Sihao, Dou, Rongzhang, Zhong, Panyi, Huang, Guoquan, Han, Lei, Zheng, Jinsen, Zhang, Xinyao, Wang, Shuyi, Xiong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043498/
https://www.ncbi.nlm.nih.gov/pubmed/35447413
http://dx.doi.org/10.1016/j.redox.2022.102312