New quinoxaline compounds as DPP-4 inhibitors and hypoglycemics: design, synthesis, computational and bio-distribution studies

The current work represents the design and synthetic approaches of a new set of compounds 6–10 bearing the 1,4-dimethyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide scaffold. The biological evaluation revealed that most of the new compounds were promising selective dipeptidyl peptidase-IV (...

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Detalles Bibliográficos
Autores principales: Syam, Yasmin M., Anwar, Manal M., Abd El-Karim, Somaia S., Elseginy, Samia A., Essa, Basma M., Sakr, Tamer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043576/
https://www.ncbi.nlm.nih.gov/pubmed/35494381
http://dx.doi.org/10.1039/d1ra06799k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043576/
https://www.ncbi.nlm.nih.gov/pubmed/35494381
http://dx.doi.org/10.1039/d1ra06799k

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