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Evaluation of enzymatic and magnetic properties of γ-glutamyl-[1-(13)C]glycine and its deuteration toward longer retention of the hyperpolarized state

Dynamic nuclear polarization (DNP) is an emerging cutting-edge method of acquiring metabolic and physiological information in vivo. We recently developed γ-glutamyl-[1-(13)C]glycine (γ-Glu-[1-(13)C]Gly) as a DNP nuclear magnetic resonance (NMR) molecular probe to detect γ-glutamyl transpeptidase (GG...

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Detalles Bibliográficos
Autores principales: Kondo, Yohei, Saito, Yutaro, Elhelaly, Abdelazim Elsayed, Hyodo, Fuminori, Nishihara, Tatsuya, Itoda, Marino, Nonaka, Hiroshi, Matsuo, Masayuki, Sando, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043577/
https://www.ncbi.nlm.nih.gov/pubmed/35496407
http://dx.doi.org/10.1039/d1ra07343e