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New triterpenes from Cimicifuga yunnanensis down-regulating the mRNA expression of CD147, MMP-2, and MMP-9

Eleven new 9,19-cycloartane triterpenes (1–9, 11–12) and one undescribed lanostane-type aglycone (10) were identified from the aerial parts of Cimicifuga yunnanensis. The new structures were elucidated by analysis of spectroscopic data. Compounds 3–5, 7–9, and 11, without obvious cytotoxicity at 50...

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Detalles Bibliográficos
Autores principales: Lu, Ni-Hong, Li, Jie, Yang, Yong-Rui, Liu, Hong-Lu, Du, Ying-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043592/
https://www.ncbi.nlm.nih.gov/pubmed/35494395
http://dx.doi.org/10.1039/d1ra07828c