Application of an Accessible Interface for Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation

Regulatory toxicology testing has traditionally relied on in vivo methods to inform decision-making. However, scientific, practical, and ethical considerations have led to an increased interest in the use of in vitro and in silico methods to fill data gaps. While in vitro experiments have the advant...

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Detalles Bibliográficos
Autores principales: Hines, David E., Bell, Shannon, Chang, Xiaoqing, Mansouri, Kamel, Allen, David, Kleinstreuer, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043603/
https://www.ncbi.nlm.nih.gov/pubmed/35496281
http://dx.doi.org/10.3389/fphar.2022.864742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043603/
https://www.ncbi.nlm.nih.gov/pubmed/35496281
http://dx.doi.org/10.3389/fphar.2022.864742

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