Cargando…
Application of an Accessible Interface for Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation
Regulatory toxicology testing has traditionally relied on in vivo methods to inform decision-making. However, scientific, practical, and ethical considerations have led to an increased interest in the use of in vitro and in silico methods to fill data gaps. While in vitro experiments have the advant...
Autores principales: | Hines, David E., Bell, Shannon, Chang, Xiaoqing, Mansouri, Kamel, Allen, David, Kleinstreuer, Nicole |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043603/ https://www.ncbi.nlm.nih.gov/pubmed/35496281 http://dx.doi.org/10.3389/fphar.2022.864742 |
Ejemplares similares
-
Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues
por: Chang, Xiaoqing, et al.
Publicado: (2022) -
Evaluation and Optimization of Pharmacokinetic Models for in Vitro to in Vivo Extrapolation of Estrogenic Activity for Environmental Chemicals
por: Casey, Warren M., et al.
Publicado: (2018) -
Evaluation of Inhalation Exposures and Potential Health Impacts of Ingredient Mixtures Using in vitro to in vivo Extrapolation
por: Zhang, Jingjie, et al.
Publicado: (2022) -
A Computational Workflow for Probabilistic Quantitative in Vitro to in Vivo Extrapolation
por: McNally, Kevin, et al.
Publicado: (2018) -
Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro–in vivo extrapolation
por: Algharably, Engi Abdelhady, et al.
Publicado: (2023)