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On the development of B-Raf inhibitors acting through innovative mechanisms
B-Raf is a protein kinase participating to the regulation of many biological processes in cells. Several studies have demonstrated that this protein is frequently upregulated in human cancers, especially when it bears activating mutations. In the last years, few ATP-competitive inhibitors of B-Raf h...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043679/ https://www.ncbi.nlm.nih.gov/pubmed/35529278 http://dx.doi.org/10.12688/f1000research.108761.2 |