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Preservation of heparin-binding EGF-like growth factor activity on heparin-modified poly(N-isopropylacrylamide)-grafted surfaces

A heparin-modified poly(N-isopropylacrylamide) (PIPAAm)-grafted surface bound with heparin-binding epidermal growth factor-like growth factor (HB-EGF) was able to culture hepatocytes maintaining high albumin secretion and high expression of hepatocyte-specific genes. However, the activity of HB-EGF...

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Detalles Bibliográficos
Autores principales: Kobayashi, Jun, Arisaka, Yoshinori, Yui, Nobuhiko, Yamato, Masayuki, Okano, Teruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043771/
https://www.ncbi.nlm.nih.gov/pubmed/35496401
http://dx.doi.org/10.1039/d1ra07317f