Bicyclo[6.1.0]nonyne carboxylic acid for the production of stable molecular probes

Bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN alcohol) is the most prominent strained-alkyne scaffold in chemical biology. Described herein is the synthesis of an oxidized analogue – BCN acid – whose facile functionalization via amide bond formation yields more stable derivatives than the classically enc...

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Detalles Bibliográficos
Autores principales: Rady, Tony, Mosser, Michel, Nothisen, Marc, Erb, Stephane, Dovgan, Igor, Cianférani, Sarah, Wagner, Alain, Chaubet, Guilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043778/
https://www.ncbi.nlm.nih.gov/pubmed/35494363
http://dx.doi.org/10.1039/d1ra07905k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043778/
https://www.ncbi.nlm.nih.gov/pubmed/35494363
http://dx.doi.org/10.1039/d1ra07905k

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