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Oligomeric procyanidins inhibit insulin fibrillation by forming unstructured and off-pathway aggregates
β-sheet-rich amyloid fibril or aggregate accumulation has been implicated in a number of human diseases. Numerous studies demonstrate that natural polyphenols decrease the risk of degenerative diseases and inhibit in vitro amyloid formation. However, the molecular mechanism for the anti-amyloidogene...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043779/ https://www.ncbi.nlm.nih.gov/pubmed/35496438 http://dx.doi.org/10.1039/d1ra05397c |