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Development of fructose-1,6-bisphosphate aldolase enzyme peptide mimics as biocatalysts in direct asymmetric aldol reactions

This study describes the design and synthesis of mimetic peptides modelled on the catalytic active site of the fructose-1,6-bisphosphate aldolase (FBPA) enzyme. The synthesized peptides consisting of the turn motifs and catalytic site amino acids of FBPA enzyme were evaluated for catalytic activity...

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Detalles Bibliográficos
Autores principales: Peme, Thabo, Brady, Dean, Juma, Wanyama, Makatini, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043830/
https://www.ncbi.nlm.nih.gov/pubmed/35494350
http://dx.doi.org/10.1039/d1ra06616a