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SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear
Shear-induced platelet aggregation (SIPA) occurs under elevated shear rates (10 000 s(−1)) found in stenotic coronary and carotid arteries. The pathologically high shear environment can lead to occlusive thrombosis by SIPA from the interaction of nonactivated platelets and von Willebrand factor (VWF...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043924/ https://www.ncbi.nlm.nih.gov/pubmed/34933342 http://dx.doi.org/10.1182/bloodadvances.2021005692 |