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SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear
Shear-induced platelet aggregation (SIPA) occurs under elevated shear rates (10 000 s(−1)) found in stenotic coronary and carotid arteries. The pathologically high shear environment can lead to occlusive thrombosis by SIPA from the interaction of nonactivated platelets and von Willebrand factor (VWF...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Hematology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043924/ https://www.ncbi.nlm.nih.gov/pubmed/34933342 http://dx.doi.org/10.1182/bloodadvances.2021005692 |