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SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear

Shear-induced platelet aggregation (SIPA) occurs under elevated shear rates (10 000 s(−1)) found in stenotic coronary and carotid arteries. The pathologically high shear environment can lead to occlusive thrombosis by SIPA from the interaction of nonactivated platelets and von Willebrand factor (VWF...

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Detalles Bibliográficos
Autores principales:	Liu, Zixiang Leonardo, Bresette, Christopher, Aidun, Cyrus K., Ku, David N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Hematology 2022
Materias:	Thrombosis and Hemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043924/ https://www.ncbi.nlm.nih.gov/pubmed/34933342 http://dx.doi.org/10.1182/bloodadvances.2021005692

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