Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2

Although it is known that the expression and activity of sirtuin 1 (SIRT1) significantly decrease in doxorubicin (DOX)-induced cardiomyopathy, the role of interaction between SIRT1 and sestrin 2 (SESN2) is largely unknown. In this study, we investigated whether SESN2 could be a crucial target of SIR...

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Detalles Bibliográficos
Autores principales: Wang(a), Jie, Tang, Yufeng, Zhang, Jingjing, Wang(b), Jie, Xiao, Mengjie, Lu, Guangping, Li, Jiahao, Liu, Qingbo, Guo, Yuanfang, Gu, Junlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043985/
https://www.ncbi.nlm.nih.gov/pubmed/35452917
http://dx.doi.org/10.1016/j.redox.2022.102310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043985/
https://www.ncbi.nlm.nih.gov/pubmed/35452917
http://dx.doi.org/10.1016/j.redox.2022.102310

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