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Cardiac SIRT1 ameliorates doxorubicin-induced cardiotoxicity by targeting sestrin 2

Although it is known that the expression and activity of sirtuin 1 (SIRT1) significantly decrease in doxorubicin (DOX)-induced cardiomyopathy, the role of interaction between SIRT1 and sestrin 2 (SESN2) is largely unknown. In this study, we investigated whether SESN2 could be a crucial target of SIR...

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Detalles Bibliográficos
Autores principales:	Wang(a), Jie, Tang, Yufeng, Zhang, Jingjing, Wang(b), Jie, Xiao, Mengjie, Lu, Guangping, Li, Jiahao, Liu, Qingbo, Guo, Yuanfang, Gu, Junlian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043985/ https://www.ncbi.nlm.nih.gov/pubmed/35452917 http://dx.doi.org/10.1016/j.redox.2022.102310

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