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Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice

From genetic and etiological studies, autoimmune mechanisms underlying schizophrenia are suspected; however, the details remain unclear. In this study, we describe autoantibodies against neural cell adhesion molecule (NCAM1) in patients with schizophrenia (5.4%, cell-based assay; 6.7%, ELISA) in a J...

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Detalles Bibliográficos
Autores principales: Shiwaku, Hiroki, Katayama, Shingo, Kondo, Kanoh, Nakano, Yuri, Tanaka, Hikari, Yoshioka, Yuki, Fujita, Kyota, Tamaki, Haruna, Takebayashi, Hironao, Terasaki, Omi, Nagase, Yukihiro, Nagase, Teruyoshi, Kubota, Tetsuo, Ishikawa, Kinya, Okazawa, Hitoshi, Takahashi, Hidehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043990/
https://www.ncbi.nlm.nih.gov/pubmed/35492247
http://dx.doi.org/10.1016/j.xcrm.2022.100597