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LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men

The gastric hormone ghrelin stimulates food intake and increases plasma glucose through activation of the growth hormone secretagogue receptor (GHSR). Liver-expressed antimicrobial peptide 2 (LEAP2) has been proposed to inhibit actions of ghrelin through inverse effects on GHSR activity. Here, we in...

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Detalles Bibliográficos
Autores principales: Hagemann, Christoffer A., Jensen, Malene S., Holm, Stephanie, Gasbjerg, Lærke S., Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens J., Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel B., Holst, Birgitte, Knop, Filip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043997/
https://www.ncbi.nlm.nih.gov/pubmed/35492241
http://dx.doi.org/10.1016/j.xcrm.2022.100582