Solution-phase synthesis of oligodeoxyribonucleotides using the H-phosphonate method with N-unprotected 5′-phosphite monomers

Recent advances in nucleic acid therapeutics increase the requirements for developing efficient methods for the chemical synthesis of oligodeoxyribonucleotides (ODNs). In this study, we report a new approach for the solution-phase synthesis of ODNs using the H-phosphonate method with N-unprotected 5...

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Detalles Bibliográficos
Autores principales: Matsuda, Hiromasa, Yoshida, Erina, Shinoda, Takaaki, Sato, Kazuki, Hara, Rintaro Iwata, Wada, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044012/
https://www.ncbi.nlm.nih.gov/pubmed/35498072
http://dx.doi.org/10.1039/d1ra06619f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044012/
https://www.ncbi.nlm.nih.gov/pubmed/35498072
http://dx.doi.org/10.1039/d1ra06619f

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