Chemical synthesis, inhibitory activity and molecular mechanism of 1-deoxynojirimycin–chrysin as a potent α-glucosidase inhibitor

Hyperglycemia can be efficaciously regulated by inhibiting α-glucosidase activity and this is regarded as an effective strategy to treat type 2 diabetes. 1-Deoxynojimycin, an α-glucosidase inhibitor, can penetrate cells rapidly to potently inhibit α-glucosidase in a competitive manner. However, the...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Zhang, Yueyue, Huang, Gaiqun, Xin, Xiangdong, Tang, Liumei, Li, Hao, Lee, Kwang Sik, Jin, Byung Rae, Gui, Zhongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044198/
https://www.ncbi.nlm.nih.gov/pubmed/35493254
http://dx.doi.org/10.1039/d1ra07753h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044198/
https://www.ncbi.nlm.nih.gov/pubmed/35493254
http://dx.doi.org/10.1039/d1ra07753h

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