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Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay

Human Suv3 is a unique homodimeric helicase that constitutes the major component of the mitochondrial degradosome to work cooperatively with exoribonuclease PNPase for efficient RNA decay. However, the molecular mechanism of how Suv3 is assembled into a homodimer to unwind RNA remains elusive. Here,...

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Detalles Bibliográficos
Autores principales: Jain, Monika, Golzarroshan, Bagher, Lin, Chia‐Liang, Agrawal, Sashank, Tang, Wei‐Hsuan, Wu, Chiu‐Ju, Yuan, Hanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044407/
https://www.ncbi.nlm.nih.gov/pubmed/35481630
http://dx.doi.org/10.1002/pro.4312