Design, synthesis, docking study and anticancer evaluation of new trimethoxyphenyl pyridine derivatives as tubulin inhibitors and apoptosis inducers

Microtubules have become an appealing target for anticancer drug development including mainly colchicine binding site inhibitors (CBSIs). A new series of novel trimethoxypyridine derivatives were designed and synthesized as tubulin targeting agents. In vitro anti-proliferative activities of the test...

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Detalles Bibliográficos
Autores principales: Hagras, Mohamed, Mandour, Asmaa A., Mohamed, Esraa A., Elkaeed, Eslam B., Gobaara, Ibrahim M. M., Mehany, Ahmed B. M., Ismail, Nasser S. M., Refaat, Hanan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044549/
https://www.ncbi.nlm.nih.gov/pubmed/35494162
http://dx.doi.org/10.1039/d1ra07922k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044549/
https://www.ncbi.nlm.nih.gov/pubmed/35494162
http://dx.doi.org/10.1039/d1ra07922k

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