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PINK1 mediated mitophagy attenuates early apoptosis of gingival epithelial cells induced by high glucose

BACKGROUND: Oxidative stress mediated by hyperglycemia damages cell-reparative processes such as mitophagy. Down-regulation of mitophagy is considered to be a susceptible factor for diabetes mellitus (DM) and its complications. However, the role of mitophagy in DM-associated periodontitis has not be...

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Detalles Bibliográficos
Autores principales: Zhu, Chunhui, Zhao, Ying, Pei, Dandan, Liu, Zhongbo, Liu, Jin, Li, Ye, Yu, Shuchen, Ma, Lingyan, Sun, Junyi, Li, Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044577/
https://www.ncbi.nlm.nih.gov/pubmed/35473620
http://dx.doi.org/10.1186/s12903-022-02167-5