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Tryptophan hydroxylase 1 drives glioma progression by modulating the serotonin/L1CAM/NF-κB signaling pathway

BACKGROUND: Glioma is one of the main causes of cancer-related mortality worldwide and is associated with high heterogeneity. However, the key players determining the fate of glioma remain obscure. In the present study, we shed light on tumor metabolism and aimed to investigate the role of tryptopha...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Guo, Zhangchao, Xie, Qiangli, Zhong, Chuanhong, Gao, Xiangyu, Yang, Qiumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044587/
https://www.ncbi.nlm.nih.gov/pubmed/35473609
http://dx.doi.org/10.1186/s12885-022-09569-2