Angong Niuhuang Wan reduces hemorrhagic transformation and mortality in ischemic stroke rats with delayed thrombolysis: involvement of peroxynitrite-mediated MMP-9 activation

BACKGROUND: Hemorrhagic transformation (HT) is a common complication of delayed tissue plasminogen activator (t-PA) treatment for ischemic stroke. Peroxynitrite plays an important role in the breakdown of blood–brain barrier (BBB) and the development of HT. We tested the hypothesis that Angong Niuhu...

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Detalles Bibliográficos
Autores principales: Chen, Hansen, Luo, Yunxia, Tsoi, Bun, Gu, Bing, Qi, Suhua, Shen, Jiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044615/
https://www.ncbi.nlm.nih.gov/pubmed/35477576
http://dx.doi.org/10.1186/s13020-022-00595-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044615/
https://www.ncbi.nlm.nih.gov/pubmed/35477576
http://dx.doi.org/10.1186/s13020-022-00595-7

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