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Sequence-specific recognition of a coding segment of human DACH1 gene via short pyrimidine/purine oligonucleotides

With growing in vivo evidence of the roles of triplexes in biological processes, oligonucleotide-directed targeting of double-helical DNA for selective modulation of gene functions has become imperative in their therapeutic aspects. This study comprises a comparative investigation of 17-mer Py- and...

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Detalles Bibliográficos
Autores principales: Khan, Shoaib, Singh, Anju, Nain, Nishu, Gulati, Srishty, Kukreti, Shrikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044637/
https://www.ncbi.nlm.nih.gov/pubmed/35494143
http://dx.doi.org/10.1039/d1ra06604h