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Cerebrospinal fluid lactate levels along the Alzheimer’s disease continuum and associations with blood-brain barrier integrity, age, cognition, and biomarkers

BACKGROUND: Cerebrospinal fluid (CSF) lactate levels have been suggested to be associated with disease severity and progression in several neurological diseases as an indicator of impaired energy metabolism, neuronal death, or microglial activation. Few studies have examined CSF lactate levels in de...

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Detalles Bibliográficos
Autores principales: Zebhauser, Paul Theo, Berthele, Achim, Goldhardt, Oliver, Diehl-Schmid, Janine, Priller, Josef, Ortner, Marion, Grimmer, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044672/
https://www.ncbi.nlm.nih.gov/pubmed/35473756
http://dx.doi.org/10.1186/s13195-022-01004-9