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Breaking the Restriction Barriers and Applying CRISPRi as a Gene Silencing Tool in Pseudoclostridium thermosuccinogenes

Pseudoclostridium thermosuccinogenes is a thermophilic bacterium capable of producing succinate from lignocellulosic-derived sugars and has the potential to be exploited as a platform organism. However, exploitation of P. thermosuccinogenes has been limited partly due to the genetic inaccessibility...

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Detalles Bibliográficos
Autores principales: Ganguly, Joyshree, Martin-Pascual, Maria, Montiel González, Diego, Bulut, Alkan, Vermeulen, Bram, Tjalma, Ivo, Vidaki, Athina, van Kranenburg, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044749/
https://www.ncbi.nlm.nih.gov/pubmed/35456750
http://dx.doi.org/10.3390/microorganisms10040698