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Cell type-specific response of colon cancer tumor cell lines to oncolytic HSV-1 virotherapy in hypoxia

BACKGROUND: Novel strategies are required since the hypoxic tumor microenvironment is one of the important impediments for conventional cancer therapy. High mobility group box 1 (HMGB1) protein can block aerobic respiration in cancer cells. We hypothesized that HMGB1could also kill the colorectal ca...

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Detalles Bibliográficos
Autores principales: Shayan, Sara, Arashkia, Arash, Bahramali, Golnaz, Abdoli, Asghar, Nosrati, Mohammad Sadegh Shams, Azadmanesh, Kayhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044800/
https://www.ncbi.nlm.nih.gov/pubmed/35477503
http://dx.doi.org/10.1186/s12935-022-02564-4