Cargando…

HIF1α-SP1 interaction disrupts the circ-0001875/miR-31-5p/SP1 regulatory loop under a hypoxic microenvironment and promotes non-small cell lung cancer progression

BACKGROUND: Circular RNAs (circRNAs) play an important role in the progression of non-small cell lung cancer (NSCLC), especially under tumor hypoxia. However, the precise functions and underlying mechanisms of dysregulated circRNAs in NSCLC are largely unknown. METHODS: High-throughput RNA sequencin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dong, Chen, Tingting, Zhao, Xuanna, Huang, Dan, Huang, Jiawei, Huang, Yujie, Huang, Qiu, Liang, Zhu, Chen, Chunyuan, Chen, Min, Li, Dongming, Wu, Bin, Li, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044860/
https://www.ncbi.nlm.nih.gov/pubmed/35473752
http://dx.doi.org/10.1186/s13046-022-02336-y