Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data

BACKGROUND: Revealing the gene targets of distal regulatory elements is challenging yet critical for interpreting regulome data. Experiment-derived enhancer-gene links are restricted to a small set of enhancers and/or cell types, while the accuracy of genome-wide approaches remains elusive due to th...

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Detalles Bibliográficos
Autores principales: Qin, Tingting, Lee, Christopher, Li, Shiting, Cavalcante, Raymond G., Orchard, Peter, Yao, Heming, Zhang, Hanrui, Wang, Shuze, Patil, Snehal, Boyle, Alan P., Sartor, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044877/
https://www.ncbi.nlm.nih.gov/pubmed/35473573
http://dx.doi.org/10.1186/s13059-022-02668-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044877/
https://www.ncbi.nlm.nih.gov/pubmed/35473573
http://dx.doi.org/10.1186/s13059-022-02668-0

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